SP1 amplifies the effects of cellular proliferation via the Wnt/β-catenin pathway in colon development and cancer
Ankita Sharma, Greg Jude Dsilva, Saurabh J. Pradhan, Sudiksha Mishra, Kirankumar Santhakumar, Sanjeev Galande
This study shows that SP1 enhances Wnt/β-catenin pathway effects on cell proliferation in colon development and cancer, with conserved roles in both contexts.
bioRxiv · Jun 5, 2025 · PreprintCancer Biology