The ALS- and FTD-associated proteins Annexin A11 and CHMP2B act sequentially in membrane repair
Catherine M Heffner, Georgina P. Starling, Lorian Cobra Straker, Philippa C. Hawes, Adrian M. Isaacs, Jeremy Graham Carlton
The paper investigates the sequential roles of Annexin A11 and CHMP2B in membrane repair, showing Annexins act first to seal damage while ESCRT-III removes damaged membranes.
Developmental Cell · Jun 25, 2026Peer-reviewedCell Biology