Author

Luis Martínez‐Gil

Universitat de ValènciaORCID 0000-0002-9076-7760Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein sequence· 2 Research Focus:differential expression· 1 Assay:protein structure· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Ismael MingarroiD· 3 shared Maria Jesús García‐MurriaiD· 3 shared Gunnar von HEIJNEiD· 2 shared Josep Alonso-Romero· 2 shared Juan Ortiz‐MateuiD· 2 shared Manuel M. Sánchez del PinoiD· 2 shared Ana Isabel Avilés‐AlíaiD· 1 shared Ane MetolaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMolecular Biology

Ismael MingarroORCID

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3 papers

Recent·Most cited

SARS-CoV-2 membrane protein biogenesis

Juan Ortiz‐Mateu, Guy Pearson, Marina Rius-Salvador, Shiva Sedighian, Ànna Pavlova, Josep Alonso-Romero, José M. Acosta‐Cáceres, Ane Metola, Maria Jesús García‐Murria, Mark J. Skehel, James C. Gumbart, Jeremy Graham Carlton, Gunnar von HEIJNE, Manuel M. Sánchez del Pino, Luis Martínez‐Gil, Ismael Mingarro

This study investigates the biogenesis of the SARS-CoV-2 M protein, revealing key steps in its insertion, folding, and oligomerization.

bioRxiv · Jan 20, 2026 · PreprintMolecular Biology

The sequence and structural integrity of the SARS-CoV-2 Spike protein transmembrane domain is crucial for viral entry

Juan Ortiz‐Mateu, Diego Belda, Ana Isabel Avilés‐Alía, Josep Alonso-Romero, Maria Jesús García‐Murria, Ismael Mingarro, Ron Geller, Luis Martínez‐Gil

This study investigates the functional role of the SARS-CoV-2 Spike protein transmembrane domain in viral entry and identifies key sequence and structural features critical for its activity.

Communications Biology · Nov 17, 2025Peer-reviewedMolecular Biology

Sequence-dependent scale for translocon-mediated insertion of interfacial helices in membranes

Brayan Grau, Rian C. Kormos, Manuel Bañó‐Polo, Kehan Chen, Maria Jesús García‐Murria, Fatlum Hajredini, Manuel M. Sánchez del Pino, Hyunil Jo, Luis Martínez‐Gil, Gunnar von HEIJNE, William F. DeGrado, Ismael Mingarro

The paper develops a method to determine sequence-dependent propensities for membrane protein insertion states using glycosylation patterns and UMAP analysis.

Science Advances · Feb 19, 2025Peer-reviewedMolecular Biology