Author
Abramson Cancer CenterORCID 0000-0002-7274-811XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Meghan T. Logun, Sabrina L. Begley, Kelly Hicks…·Donald M. O’Rourke
The paper shows that delivering CAR-T cells via a hydrogel in the resection cavity improves survival in mice with recurrent glioblastoma.
Meghan T. Logun, Xin Wang, Yusha Y. Sun…·Donald M. O’Rourke
The paper shows that patient-derived glioblastoma organoids can reflect CAR-T cell treatment responses in real-time, correlating with clinical outcomes in patients.
Nannan Li, Jesse L. Rodriguez, Yibo Yin…·Donald M. O’Rourke
This paper develops a tri-modular CAR T cell construct with a dominant-negative TGF-β receptor II to overcome GBM resistance by enhancing T cell function and efficacy in a preclinical model.