Holly J. Whitfield

An integrated single cell and spatial omics atlas of human prenatal development

Human Developmental Cell Atlas integrates ~4.6 million cells/nuclei from 4-22 post-conception weeks into 454 refined cell types and maps 114 spatial niches across 6PCW whole-embryo sections.

Single cell transcriptional evolution of myeloid leukaemia of Down syndrome

The paper examines the transcriptional evolution of myeloid leukaemia in Down syndrome by analyzing single-cell RNA sequencing data from patient samples and fetal tissues.

A developmental cell atlas of the human thyroid gland

This study creates a developmental cell atlas of the human thyroid gland using single-cell sequencing, revealing cell type heterogeneity and its implications in thyroid disorders and cancer.

vissE: A versatile tool to identify and visualise higher-order molecular phenotypes from functional enrichment analysis

vissE identifies and visualizes higher-order molecular phenotypes from functional enrichment analysis by summarizing redundancies into biological themes.

Identification of cell types, states and programs by learning gene set representations

scDECAF identifies cell types, states, and programs in single-cell data by learning gene set representations, showing effectiveness in disease and immune response contexts.