Magdalena I. Ivanova

Backbone Thioamide Substitution Enhances the Activity of Short Peptides in Modulating the Aggregation of α-Synuclein

This study shows that modifying the backbone of a minimal NAC-derived peptide with thioamide enhances its ability to modulate α-synuclein aggregation, while N-methylation inhibits it.

Differential Effects of Ganglioside Lipids on the Conformation and Aggregation of Islet Amyloid Polypeptide

This study investigates how different gangliosides affect hIAPP aggregation and structure, finding that lipid-peptide ratios and charge/headgroup size influence aggregation and conformation.

Nanodisc reconstitution and characterization of amyloid-β precursor protein C99

This study reconstitutes and characterizes the C99 domain of APP in nanodiscs using multiple biophysical methods.

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

This study compares the phase separation and aggregation properties of three brain-expressed ubiquilins, finding differences in their condensate formation and aggregation propensity.