Author

Nathaniel Safren

Northwestern UniversityORCID 0000-0003-4866-4837Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra B. SutteriD· 2 shared Henry Lauris PaulsoniD· 2 shared Lisa M. SharkeyiD· 2 shared Amit S. Pithadia· 1 shared Bryce Trotter· 1 shared Carley Snoznik· 1 shared Casey DaltoniD· 1 shared Chengxin ZhangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Alexandra B. SutterORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of NeurosciencePeer-reviewedDec 10, 2025

Ubiquitin Proteasome System Components, RAD23A and USP13, Modulate TDP-43 Solubility and Neuronal Toxicity

Casey Dalton, Jelena Mojsilovic‐Petrovic, Nathaniel Safren…·Robert Gordon Kalb

This study identifies RAD23A and USP13 as modifier genes that enhance TDP-43 solubility and reduce neuronal toxicity in ALS models.

2 citations

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NeuroscienceCellular and Molecular Life SciencesPeer-reviewedMar 1, 2022

RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control

Harihar Milaganur Mohan, Hanna Trzeciakiewicz, Amit S. Pithadia…·Lisa M. Sharkey

This study identifies RTL8 as a novel UBQLN2 interactor that promotes its nuclear translocation and subnuclear localization in protein quality control.

21 citations

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NeuroscienceScientific ReportsPeer-reviewedJan 11, 2021

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

Julia E. Gerson, Hunter Linton, Jiazheng Xing…·Magdalena I. Ivanova

This study compares the phase separation and aggregation properties of three brain-expressed ubiquilins, finding differences in their condensate formation and aggregation propensity.

24 citations

humanstatistical model

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