Author

Xiaofeng Ding

Tulane UniversityORCID 0000-0002-7319-6441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jay K. KollsiD· 3 shared Yilin Chen· 3 shared Jefferson Fernandes EvangelistaiD· 2 shared Mohammad IslamuddiniD· 2 shared Robert V. BlairiD· 2 shared Xuebin QiniD· 2 shared Ahmad A. SaiediD· 1 shared Amrita Kumar· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Jay K. KollsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IRF7 deficiency increases disease severity independently of TLR7 recognition in Influenza A infection in mice

Ana Karina Nisperuza Vidal, Chenxiao Wang, Michaela J. Allen, Xiaofeng Ding, Jefferson Fernandes Evangelista, Yilin Chen, M Khatun, Amrita Kumar, Calder R. Ellsworth, Mohammad Islamuddin, Robert V. Blair, Suryaprakash R. Sambhara, Jay K. Kolls, Derek A. Pociask, Xuebin Qin

This study shows that IRF7 deficiency worsens influenza A disease in mice, independent of TLR7, by impairing early interferon responses and adaptive immunity.

bioRxiv · May 26, 2026 · PreprintImmunology

Rapid Podocyte ablation Causes Acute Renal Tubule Cell Necrosis and Interstitial Fibrosis

Yilin Chen, Mohammad Islamuddin, Xiaofeng Ding, Jefferson Fernandes Evangelista, Avi Salomon, Gabriella M Hidalgo, Shumei Liu, Cecily C. Midkiff, Ryousuke Satou, Jia L. Zhuo, Jay K. Kolls, Vecihi Batuman, Rhea Bhargava, Robert V Blair, Xuebin Qin

This study uses a mouse model to show that rapid podocyte ablation leads to acute renal tubule cell necrosis, interstitial fibrosis, and renal failure.

bioRxiv · Mar 23, 2026 · PreprintPathology

Persistent Activation of Monocytes/Macrophages and Cell Senescence in SIV-Infected Macaques on ART

Yilin Chen, Xiaofeng Ding, Sonalika Ray, Siva Thirugnanam, Robert V. Blair, Ahmad A. Saied, Sergiy Sukhanov, Jay K. Kolls, W. Y. KIM, Patrice Delafontaine, Jay Rappaport, Xuebin Qin, Namita Rout

This study shows that long-term ART in SIV-infected macaques reduces acute inflammation but maintains chronic macrophage and TLR-driven inflammation linked to vascular damage and aging.

Frontiers in Immunology · Mar 12, 2026Peer-reviewedImmunology