A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity
Nikolaj Pagh Kristensen, Thanos Tsaktanis, Sina Frischholz, Jasim Kada Benotmane, Lucia Klotz, Philipp Hilgendorf, M. Grotz, Mariana Sousa, Lasse Frank Voss, Stefan Schattgen, Vanessa Lang, Hannah Reimann, Cosima Storr, Roland Lang, Bernd M. Spriewald, , Kilian Schober
The paper identifies an EBV-specific T cell program in MS patients that contributes to CNS autoimmunity through B cell and myeloid cell activation.
bioRxiv · Oct 1, 2026 · PreprintImmunology