Emirhan Nemutlu

Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism

This study shows pathogenic bacteria disrupt cerebral organoid structure and energy metabolism by altering glycolysis and increasing pentose phosphate pathway activity.

Metabolomic analysis of the effect of endocannabinoid metabolism inhibition in ovalbumin-induced allergic airway inflammation in Guinea pigs

Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimers mouse model

The paper shows that partial inhibition of mitochondrial complex I protects against neurodegeneration in Alzheimer's mice by improving energy homeostasis, synaptic function, and reducing inflammation.