Jean‐François Eléouët

This study characterizes liquid-liquid phase separation driven by RSV proteins and RNA, identifying key interactions and stoichiometric requirements for condensate formation.

This study shows that RSV forms condensates by pre-assembling replication centers within viral particles, explaining infection heterogeneity and enabling efficient replication without requiring pre-existing condensates.

This study identifies R27 methylation as a regulator of HRSV nucleocapsid structure and replication through molecular dynamics and cryo-EM analyses.

This study investigates plitidepsin's antiviral potential against HRSV, finding it inhibits replication but also causes cellular translation inhibition and eEF1A degradation, suggesting risks for antiviral use.

This paper identifies a dual interaction between RSV NS1 and MED25 ACID domain that suppresses antiviral responses by blocking transcription factor access to MED25.

The paper analyzes RSV RNA structures and finds conserved motifs that may impact viral replication, using bioinformatics and experimental methods.