RIP3 and MLKL regulate Hepatic ER stress in alcohol-associated liver disease and pharmacological ER stress models: insights beyond necroptosis
Rakesh K. Arya, Emily Huang, Megan R. McMullen…·Laura E. Nagy
Author
Cleveland ClinicORCID 0000-0002-7393-1282Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Rakesh K. Arya, Emily Huang, Megan R. McMullen…·Laura E. Nagy
Evi Paouri, Sarah Stanko, Nadia Gasmi…·Dimitrios Davalos
This study shows that preventing microglial reactivity protects against acute and progressive neurological dysfunction and motor impairments caused by alcohol abuse in mice.
Jared Travers, Emily Huang, Megan R. McMullen…·Laura E. Nagy
The paper identifies a novel TGFβ-mt-dsRNA-stress granule axis that promotes IRF3-mediated fibrotic responses in hepatic stellate cells.
Venkateshwari Varadharajan, Iyappan Ramachandiran, William J. Massey…·Jonathan Mark Brown
This study shows that MBOAT7 loss of function in hepatocytes causes ethanol-induced liver injury by disrupting lysosomal biogenesis and autophagic flux.