Dimitrios Davalos

This study creates a single-cell transcriptomic atlas of the adult mouse dural meninges, revealing widespread sex differences across cell types, communication, and disease-related features.

This study uses chemogenetic activation of pericytes in mice to show their ability to contract capillaries and cause hypoperfusion, particularly in limbic regions.

This study shows that preventing microglial reactivity protects against acute and progressive neurological dysfunction and motor impairments caused by alcohol abuse in mice.

The paper identifies a novel TGFβ-mt-dsRNA-stress granule axis that promotes IRF3-mediated fibrotic responses in hepatic stellate cells.

The paper investigates the role of microglia in maintaining blood-brain barrier properties in health and finds that microglia are not required, but PLX5622 treatment affects endothelial cholesterol metabolism.

This study identifies lipid droplet formation in microglia as a mechanism linking amyloid-beta exposure to impaired phagocytosis in Alzheimer's disease, with DGAT2 as a therapeutic target.