Jonathan Mark Brown

This study identifies N-acyl amides from gut microbes as regulators of postprandial metabolic homeostasis by affecting host hormones, gene expression, and microbiome composition.

This study investigates how dietary fatty acids interact with gut microbiota and host metabolism to influence lipid homeostasis and cardiometabolic disease in mice.

This study shows that gut microbe-derived TMA affects circadian rhythms through the host receptor TAAR5, impacting metabolism and behavior in mice.

This study shows that MBOAT7 loss of function in hepatocytes causes ethanol-induced liver injury by disrupting lysosomal biogenesis and autophagic flux.

This study identifies GPCR targets of gut microbiota metabolites in Alzheimer's disease using multi-omics and machine learning.