Afonso C. Silva

The paper presents the first telomere-to-telomere genome for the common marmoset, revealing genomic features and a pangenome resource for biomedical research.

This study shows that early-life disruption of the medial pulvinar in marmosets leads to adult prefrontal inhibitory and cognitive deficits relevant to schizophrenia.

The paper develops a hierarchical atlas for gray-matter parcellation across multiple species, validated through cross-species comparisons and connectivity analysis.

This study develops a pipeline to generate synthetic MRI scans with anatomical variation and trains a U-Net model to segment the corpus callosum in marmosets, achieving high accuracy in both healthy and disease contexts.

This study shows that PSEN1 mutant marmoset fibroblasts exhibit multi-omic signatures similar to Alzheimer's disease in humans, highlighting sex-specific differences and disease-relevant pathways.

The paper provides open-access CAD files and software for marmoset neuroscience apparatus, reducing the need for individual lab development.

This study confirms the expression of 3R and 4R Tau isoforms and phosphorylation sites in marmoset brains, supporting their use as a model for Alzheimer's disease.

The paper identifies thalamic commissures in primates, showing they connect cortex to contralateral thalamus and exist in both healthy and malformed human brains.

This study demonstrates non-invasive blood-brain barrier disruption in marmosets using transcranial focused ultrasound with microbubbles, establishing safe and reliable parameters for preclinical applications.

This study shows that in vivo MRI can detect remyelination in a nonhuman primate model of MS with high accuracy, suggesting its potential for preclinical and clinical applications.

The paper integrates structural and functional connectivity data from marmoset brains to map functional networks, develop a deep-learning parcellation generator, and investigate structural-functional relationships.

The paper creates a 3D marmoset cortex template from 20 brains, providing probabilistic localization of cytoarchitectural areas and spatial transformations to other templates.