Kim De Keersmaecker

This paper shows that sertraline and carfilzomib work together to kill T-cell cancers by disrupting metabolism and changing the immune environment.

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

This study evaluates the feasibility and survival impact of applying the clinical standard of care to glioblastoma mouse models, showing improved outcomes when treatments are combined.