Author

Jelle Verbeeck

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Kim De KeersmaeckeriD· 3 shared Jonathan Royaert· 2 shared An CoosemansiD· 1 shared Anaïs AstieriD· 1 shared Anaís Sánchez‐CastilloiD· 1 shared Ann VankerckhoveniD· 1 shared Annalisa OcchipintiiD· 1 shared Carine FromentiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCancer Biology

Kim De KeersmaeckerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sertraline and Carfilzomib Synergize to Target T-cell Malignancies with Serine/Glycine synthesis activity via Cholesterol Dysregulation, Cellular Stress and Immune Modulation

Paulien Verstraete, Elien Heylen, Anaís Sánchez‐Castillo, João Fontela, Lies Matthys, Sofie Meykens, Óscar Herranz, Suraj Verma, Le Minh Thao Doan, Linde Van Aerschot, Jelle Verbeeck, Jonathan Royaert, Michiel Vandenbosch, Ruben Jacobs, Gabriella Dow, , Kim De Keersmaecker

This paper shows that sertraline and carfilzomib work together to kill T-cell cancers by disrupting metabolism and changing the immune environment.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

Translatome and translation dynamics analysis of a RiboCancer cell line panel reveals that leukemia-associated Rps15 mutations rewire translation through codon-specific tRNA accommodation defects.

Anaïs Astier, Marino Caruso, Stijn Vereecke, Paulo E. Santo, Coralie Capron, Carine Froment, Dana Rinaldi, David Cabrerizo Granados, Marine Leclercq, Jonathan Royaert, Jelle Verbeeck, Naomy Pasau, Laura Plassart, Daniele Pepe, Steven Verbruggen, , Kim De Keersmaecker

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

HemaSphere · Jun 1, 2026Peer-reviewedMolecular Biology

Towards more accurate preclinical glioblastoma modelling: reverse translation of clinical standard of care in a glioblastoma mouse model.

Mattéo Riva, Sien Bevers, Roxanne Wouters, Gitte Thirion, Katja Vandenbrande, Ann Vankerckhoven, Yani Berckmans, Jelle Verbeeck, Kim De Keersmaecker, An Coosemans

This study evaluates the feasibility and survival impact of applying the clinical standard of care to glioblastoma mouse models, showing improved outcomes when treatments are combined.

bioRxiv · Jun 17, 2021 · PreprintNeuroscience