The 3UTR of the orb2 gene encoding the Drosophila CPEB translation factor plays a critical role in spermatogenesis
Rudolf A. Gilmutdinov, Eugene Kozlov, Konstantin V. Yakovlev, Ludmila V. Olenina, Alexei A. Kotov, Justinn Barr, Mariya V. Zhukova, Paul D. Schedl, Yulii V. Shidlovskii
The paper investigates the role of the orb2 gene's 3UTR in Drosophila spermatogenesis by deleting it and showing that mislocalization, not reduced levels, causes differentiation defects.
Development · Sep 1, 2021Peer-reviewedDevelopmental Biology