Justinn Barr

Stability of orb mRNA in Drosophila ovaries is regulated by cis-regulatory elements in the three prime untranslated region and influences germ cell specification

This study shows that CPE motifs in the orb 3UTR regulate mRNA stability and are essential for oocyte specification in Drosophila, while their absence leads to nurse cell development.

The 3UTR of the orb2 gene encoding the Drosophila CPEB translation factor plays a critical role in spermatogenesis

The paper investigates the role of the orb2 gene's 3UTR in Drosophila spermatogenesis by deleting it and showing that mislocalization, not reduced levels, causes differentiation defects.

Single Nucleus Multiomic Profiling Reveals Age-Dynamic Regulation of Host Genes Associated with SARS-CoV-2 Infection

The paper uses single nucleus ATAC-seq and RNA-seq to show age-related changes in chromatin accessibility and gene expression linked to SARS-CoV-2 entry genes in human lung cells.