Dustin E. Bosch

The paper develops PolyProf, a method to profile polymorphic toxin systems in metagenomes, showing it predicts microbiome development and disease-related dysbiosis.

The paper identifies microbiome markers in primary colorectal cancer tumors that predict distant metastasis risk using cohort data and molecular techniques.

This study identifies Candida albicans colonization in colorectal tumors as a factor linked to reduced survival and impaired radiation response.

This paper identifies and validates non-covalent inhibitors of RGS14 GAP activity using structure-guided virtual screening and machine learning, showing improved potency and CNS penetration.