Han-Chiao Isaac Chen

This study identifies a functional dissociation in human posterior cingulate cortex, showing dorsal PCC integrates value and memory-based decisions while ventral PCC does not.

This study develops an in vivo model of human traumatic brain injury using human cortical organoids transplanted into rats, showing injury progression and neuroinflammatory responses.

This study shows that human hippocampal ripples are modulated by arousal states, occurring more frequently during low arousal periods like sleep and certain wake states.

This study uses temporal multi-modal single-cell profiling to show CAR-T cells interact dynamically with glioblastoma cells, including antigen-negative ones, and reduce their proliferation through IFN-gamma.

This study identifies beta oscillations and traveling waves as biomarkers of recovery from traumatic brain injury using intracranial electrode data.

The paper generates a molecular neuroanatomical map of the human prefrontal cortex using spatial transcriptomics and single nucleus RNA-sequencing, revealing novel spatial domains and cell-cell interactions linked to psychiatric disorders.

The paper characterizes the laminar structure of the porcine hippocampus using histology and electrophysiology, finding features similar to both rodents and primates.