ImmunologybioRxivPreprint
Bispecific Antibody Architecture and TNFRSF Target Selection Determine CD8+ T Cell Differentiation and Anti-tumour Immunity
Marcus A. Widdess, Lucy Wilkinson, Hannah J. Metcalfe…·Aymen Al‐Shamkhani
This study shows that bispecific antibody architecture and TNFRSF target selection influence CD8+ T cell differentiation and anti-tumour immunity, with 4-1BB being the most effective target.
DOI 10.64898/2026.06.19.732642