Author

Mariagrazia Talarico

Magna Graecia UniversityORCID 0000-0002-7439-3973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

Aldo QuattroneiD· 2 shared Alessandro FiorenzanoiD· 2 shared Andrea QuattroneiD· 2 shared Clara ZanninoiD· 2 shared Desirèe Valente· 2 shared Elvira Immacolata ParrottaiD· 2 shared Giorgia Lucia BenedettoiD· 2 shared Giovanni CudaiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Aldo QuattroneORCID

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2 papers

Recent·Most cited

Non-neuronal, TGF-β- extracellular matrix restructuring promotes neurodegeneration in a PSP-Richardson syndrome model

Clara Zannino, Desirèe Valente, Davide Bressan, Andreas Bruzelius, Caterina Gabriele, Stefania Scalise, Raffeale Covello, Giorgia Lucia Benedetto, Mariagrazia Talarico, Vittorio Abbonante, Andrea Quattrone, Marco Gaspari, Aldo Quattrone, Fulvio Chiacchiera, Alessandro Fiorenzano, , Elvira Immacolata Parrotta

The paper identifies TGF-β-driven extracellular matrix remodeling in vascular leptomeningeal-like cells as a driver of neurodegeneration in PSP-RS, showing therapeutic potential through pharmacological inhibition.

bioRxiv · Aug 17, 2025 · PreprintNeuroscience

Mosaic midbrain organoids: a new tool to study Progressive Supranuclear Palsy and advancing clinical neurology research

Elvira Immacolata Parrotta, Valeria Lucchino, Clara Zannino, Desirèe Valente, Stefania Scalise, Giorgia Lucia Benedetto, Maria Roberta Iazzetta, Mariagrazia Talarico, Francesco Simone Conforti, Silvia Di Agostino, Alessandro Fiorenzano, Aldo Quattrone, Giovanni Cuda, Andrea Quattrone

The paper introduces a novel iPSC-derived mosaic midbrain organoid system to model PSP-RS and demonstrates its ability to recapitulate key pathological features of the disease.

bioRxiv · Jun 3, 2024 · PreprintNeuroscience