Lucas Leclère

Targeting the cell membrane in established and emerging model organisms

The paper develops a toolkit of membrane-localising tags tested across ten animal species to identify effective signals for targeting proteins to the plasma membrane.

The evolution of an individual-like dispersive stage in colonial siphonophores

This study investigates the mechanism of eudoxid release in siphonophores, showing it involves muscle evolution and colony modification, leading to an individual-like dispersal stage that contributes to ecological success.

Whole Animal Multiplexed Single-Cell RNA-Seq Reveals Plasticity of Clytia Medusa Cell Types

The paper presents a whole-animal transcriptomic cell atlas of Clytia hemisphaerica using multiplexed scRNA-seq to study cell type plasticity under starvation.

Pattern regulation in a regenerating jellyfish

This study shows that mechanical forces, cell migration, and Wnt signaling drive rapid regeneration of the manubrium in Clytia hemisphaerica fragments.

A G-protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia

This study identifies a G-protein-coupled receptor (MIHR) in the jellyfish Clytia that mediates neuropeptide-induced oocyte maturation and shows its functional role in gamete development and spawning.

An improved whole life cycle culture protocol for the hydrozoan genetic model Clytia hemisphaerica.

This paper describes an improved culture protocol for Clytia hemisphaerica, enabling the maintenance of its entire life cycle in the lab through optimized feeding and metamorphosis induction.

A safer, urea-based in situ hybridization method improves detection of gene expression in diverse animal species

The paper introduces a urea-based in situ hybridization method that improves gene expression detection and reduces non-specific staining across multiple animal species.