Ferrán Sanz

DISGENET integrates genotype-phenotype data to support precision medicine and drug development through comprehensive, up-to-date associations and tools.

This study shows that PPAR-γ in hippocampal astrocytes can reverse memory deficits caused by early alcohol exposure in mice.

ISOTOPE identifies tumor-specific splicing-derived epitopes using RNA sequencing and mass spectrometry, showing splicing neoepitopes have higher MHC-I binding affinity in immune responders.

This study identifies shared transcriptomic changes between Alzheimer's disease and Major Depression in mice, suggesting Major Depression may be an early manifestation of Alzheimer's.

This study introduces PxEA, a network-based method to identify drugs targeting common pathways across diseases, demonstrating drug repurposing opportunities for autoimmune disorders and comorbid conditions like type 2 diabetes and Alzheimer's disease.