Author

Sadia Safi

Karlsruhe Institute of TechnologyORCID 0000-0002-7454-2799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Gary R. DavidsoniD· 1 shared Janine WesslowskiiD· 1 shared Melanie Rothley· 1 shared Michelle RottmanniD· 1 shared

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2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Gary R. DavidsonORCID

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1 paper

Recent·Most cited

BiochemistryCellsPeer-reviewedMay 30, 2025

Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions using NanoBit/BRET

Janine Wesslowski, Sadia Safi, Michelle Rottmann…·Gary R. Davidson

This study quantifies binding affinities of Wnt3a, Wnt5a, and Wnt16 to Frizzled receptors using NanoBRET in living cells, revealing LRP6's role in modulating these interactions.

2 citations

protein structurebiophysical modeling

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