Nanoscale Chromatin Imaging and Analysis (nano-ChIA) platform bridges 4-D chromatin organization with molecular function
Yue Li, Adam Eshein, Ranya K. A. Virk, Aya Eid, Wenli Wu, Jane Frederick, David VanDerway, Scott Gladstein, Kai Huang, Nicholas M. Anthony, Greta M. Bauer, Xiang Zhou, Vasundhara Agrawal, Emily M. Pujadas-Liwag, George Esteve, , Vadim Backman
The paper introduces a nano-ChIA platform that combines electron tomography and superresolution imaging to study chromatin structure and dynamics at the single-nucleosome level in live cells.
Microscopy and Microanalysis · Jul 30, 2020Peer-reviewedGenomics