Pierre Boudinot

Characterization of the IGH locus and tissue specific immunoglobulin repertoires in turbot (Scophthalmus maximus).

This study characterizes the IGH locus and tissue-specific immunoglobulin repertoires in turbot, revealing isotype-specific diversity patterns and clonotype sharing between tissues.

Insights into the genetic architecture of resistance to viral haemorrhagic septicaemia virus in rainbow trout from a genome-wide association study to in vitro CRISPR-Cas9 functional evaluation

This study identifies novel SNPs associated with VHSV resistance in rainbow trout and shows lrp1 modulates inflammatory response during infection.

Regulation of lipid metabolism is a primordial function of STING

This study shows STING regulates lipid metabolism across species, independent of its role in antiviral immunity.

High-density genome-wide association study points out major candidate genes for resistance to infectious pancreatic necrosis in rainbow trout

This study identifies candidate genes for IPN resistance in rainbow trout using a high-density genome-wide association study and Bayesian modeling.

Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot

The paper integrates multi-omics data to study the epigenomic and transcriptomic responses to viral and bacterial stimulation in turbot, identifying gene regulation patterns and chromatin state changes.

Efficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system

The paper develops an optimized lentiviral CRISPR/Cas9 protocol for efficient genome editing in Chinook salmon cells, demonstrating successful gene editing and antibiotic selection.