Tim W. Regan

This paper presents a high-quality genome assembly and tissue expression atlas for the European lobster, along with divergence time estimates and gene duplication analyses related to immunity and longevity.

The paper presents a single-nucleus transcriptomic atlas of Pacific oysters during OsHV-1 infection, identifying cell-type-specific responses and potential viral entry sites.

This study establishes an in vitro model using Pacific oyster tissue explants to replicate OsHV-1, showing that oyster source affects infection outcomes.

This paper uses Mendelian randomisation to identify potential drug targets for cardiovascular disease by analysing protein levels in plasma and PBMCs from large cohorts.

This paper presents a chromosome-scale genome assembly for the blue mussel, Mytilus edulis, using PacBio and Omni-C technologies, and uses it to study genetic variation in three related species.

This study compares ranking aggregation methods for gene lists using simulated and real data to evaluate their performance in meta-analyses.

The paper presents a chromosome-level reference genome for the European flat oyster, enabling high-resolution genomics for conservation and aquaculture.

Graphia is an open-source platform for graph-based analysis of complex biomedical data, offering visualization, transformation, and analysis tools for high-dimensional datasets.

The paper develops an optimized lentiviral CRISPR/Cas9 protocol for efficient genome editing in Chinook salmon cells, demonstrating successful gene editing and antibiotic selection.

The paper identifies 701 genes associated with human mitotic phases through transcriptomics analysis, including 205 putative cell cycle genes and 53 uncharacterised ones, with some showing novel centrosomal localization or proliferation inhibition.

The paper characterizes the metagenome of UK honey bee colonies, identifying microbial diversity and potential pathogens in their microbiota.