Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish
Valerie S. LeBleu, Jianli Dai, Susan E. Tsutakawa, Brian Alexander MacDonald, Joseph L. Alge, Malin Sund, Liang Xie, Hikaru Sugimoto, John A. Tainer, Leonard Ira Zon, Raghu Kalluri
The paper identifies structural differences in zebrafish α4 chain of type IV collagen and shows its conserved anti-angiogenic activity compared to humans.
Developmental Dynamics · Apr 1, 2023Peer-reviewedDevelopmental Biology