Author

Valerie S. LeBleu

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-6470-5374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Raghu KalluriiD· 3 shared Hikaru SugimotoiD· 2 shared Jianli DaiiD· 2 shared Kent A. Arian· 2 shared Michelle L. KirtleyiD· 2 shared Anaïs M Comptdaer· 1 shared Bingrui LiiD· 1 shared Brian Alexander MacDonaldiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

Raghu KalluriORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 20, 2026

TGF-β2-induced Snail-mediated EndMT signaling relies on both Smad-dependent and independent pathways

Valerie S. LeBleu, Bingrui Li, Anaïs M Comptdaer…·Raghu Kalluri

The paper reproduces and validates a previously reported model of TGF-β2-induced EndMT through Smad-dependent and independent pathways across multiple studies and laboratories.

DOI 10.64898/2026.08.17.745236

experimental assaybenchmarking

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ImmunologyJournal of Controlled ReleasePeer-reviewedAug 30, 2024

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

Xin Luo, Kathleen M. McAndrews, Kent A. Arian…·Raghu Kalluri

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

30 citations

mousenon-human primate

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Developmental BiologyDevelopmental DynamicsPeer-reviewedApr 1, 2023

Identification of unique α4 chain structure and conserved anti-angiogenic activity of α3NC1 type IV collagen in zebrafish

Valerie S. LeBleu, Jianli Dai, Susan E. Tsutakawa…·Raghu Kalluri

The paper identifies structural differences in zebrafish α4 chain of type IV collagen and shows its conserved anti-angiogenic activity compared to humans.

3 citations

zebrafishprotein sequence

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