Molecular BiologyACS Central SciencePeer-reviewed
To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes
Kyle I. P. Le Huray, Tobias P. Wörner, Tiago Moreira…·Frank Sobott
This paper demonstrates the use of electron-capture charge reduction (ECCR) to deconvolve heterogeneous signals in native mass spectrometry, achieving m/z values above 200,000 for large biopharmaceutical analytes.
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