Author

Zhixiang Hu

Shanghai Medical College of Fudan UniversityORCID 0000-0002-7543-8344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Hongwu Yu· 3 shared Shenglin HuangiD· 3 shared Hena ZhangiD· 2 shared Jingjing ZhaoiD· 2 shared Peng LiniD· 2 shared Qin Li· 2 shared Yan LiiD· 2 shared Yifan Wen· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

Hongwu Yu

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 27, 2025

Engineering Linear Cap-independent mRNA Vaccines with Intrinsic Adjuvanticity for Potent Cancer Immunotherapy

Hongwu Yu, Yu Yang, Peng Lin…·Shenglin Huang

This paper develops a cap-independent mRNA vaccine platform that enhances antitumor immunity through intrinsic adjuvanticity and improved in vivo expression.

DOI 10.1101/2025.10.27.684966

mousemultiome

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Cancer BiologybioRxivPreprintMar 1, 2025

Transcriptomic splicing analysis reveals a gene-independent form of TE reactivation in tumors representing unrecognized source of oncogenes and neoantigens

Ziteng Li, Yichao Bao, Qin Li…·Shenglin Huang

This paper identifies TEtrans, gene-independent transcripts from transposable elements in tumors, which act as oncogenes and neoantigens, expanding the role of TEs in cancer.

DOI 10.1101/2025.03.01.640928

humanbulk RNA-seq

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Cancer BiologyCell ReportsPeer-reviewedOct 22, 2024

RNA Splicing Junction Landscape Reveals Abundant Tumor-Specific Transcripts in Human Cancer

Qin Li, Ziteng Li, Bing Chen…·Shenglin Huang

This study analyzes RNA splicing junctions in 34,775 samples to identify 29,051 tumor-specific transcripts linked to cancer stemness, poor prognosis, and immunotherapy targets.

11 citations

humanbulk RNA-seq

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