Qin Li

Enteroviral epitope mimicry enables NK cell-mediated targeting of ASPH in hepatocellular carcinoma

The paper identifies anti-CE1 antibodies that reduce HCC incidence and mortality by mediating NK cell ADCC against ASPH-expressing tumor cells through epitope mimicry.

DEEPReditor-CMG: A deep-learning-based predictive RNA editor for crop mitochondria genomes

The paper develops DEEPReditor-CMG, a deep learning model for predicting C-to-U RNA editing sites in crop mitochondrial genomes, showing improved accuracy and uncovering evolutionary patterns.

Vagus nerve stimulation by focused ultrasound attenuates acute myocardial ischemia/reperfusion injury predominantly through cholinergic anti-inflammatory pathway

Transcriptomic splicing analysis reveals a gene-independent form of TE reactivation in tumors representing unrecognized source of oncogenes and neoantigens

This paper identifies TEtrans, gene-independent transcripts from transposable elements in tumors, which act as oncogenes and neoantigens, expanding the role of TEs in cancer.

Dopaminergic Co-transmission with Sonic Hedgehog Inhibits Expression of Abnormal Involuntary Movements

This study shows that enhancing sonic hedgehog signaling reduces L-Dopa-induced dyskinesia in Parkinson's models by targeting dopamine neurons and cholinergic interneurons.

Lysyl oxidase promotes neuronal ferroptosis exacerbating seizure-induced hippocampal damage

This study identifies lysyl oxidase as a novel inducer of ferroptosis in neurons, which exacerbates seizure-induced hippocampal damage in mice.

High glucose-induced ubiquitylation of G6PD leads to the injury of podocyte

This study shows high glucose induces ubiquitylation of G6PD via VHL, leading to ROS accumulation and podocyte injury in diabetic kidney disease.