Sarah M. Brotman

The paper shows larger eQTL studies detect more signals that colocalize with GWAS signals, improving understanding of gene-trait relationships.

The paper identifies additional eQTL signals in adipose tissue and shows they contribute to cardiometabolic traits through gene dosage effects.

This study performs a multi-ancestry GWAS for adiponectin, identifies 22 loci, and prioritizes target genes using GPScore, revealing novel genes and pathways involved in metabolic regulation.

The paper examines the association between adipose tissue ACE2 expression and cardio-metabolic risk factors, finding lower ACE2 levels linked to T2D, obesity, and inflammation-related cell type changes.

This study identifies genetic variants influencing human cortical surface area by integrating evolutionary annotations with neuroimaging genetic data, revealing recent polygenic selection on brain regions involved in language and vision.

This paper identifies 56 new type 2 diabetes loci in 433,540 East Asian individuals through a meta-analysis of GWAS data.