Peng Xu

This study identifies four resistance mechanisms to sustained auxin-inducible protein degradation in human cells and mice using the AID2 system.

This paper shows how recombining signaling motifs creates a continuous spectrum of CAR T cell phenotypes, revealing trade-offs between memory, cytotoxicity, and safety.

This paper introduces a novel CAR T cell platform using proximal T cell signaling molecules to enable Boolean logic-gated control, improving efficacy and reducing off-tumor toxicity.

This study uses proteomics to analyze dynamic phospho-signaling networks in human erythropoiesis, identifying key regulatory mechanisms and markers across differentiation stages.