Author

Judith W. Hyle

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1

Frequent Co-Authors

Beisi XuiD· 2 shared Chunliang LiiD· 2 shared Jifeng YangiD· 2 shared Qianqian LiiD· 2 shared Shaela Fields· 2 shared Byoung-Kyu ChoiD· 1 shared Charles J. SherriD· 1 shared Frédérique ZindyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Beisi XuORCID

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2 papers

Recent·Most cited

Chemokine-Dependent Natural Killer Cells Prevent Pulmonary Metastasis in a Newly Established Mouse Osteosarcoma Model

Jifeng Yang, Frédérique Zindy, Shaela Fields, Judith W. Hyle, Laura J. Janke, Qianqian Li, Beisi Xu, Qiong Zhang, Gang Wu, Ti‐Cheng Chang, Monika Wierdl, Lillian M. Guenther, Linda M. Hendershot, Martine F. Roussel, Charles J. Sherr, Chunliang Li

This study identifies CCL2 as a chemokine that limits osteosarcoma metastasis via NK cell signaling in a mouse model.

bioRxiv · Jul 20, 2026 · PreprintCancer Biology

Deciphering acquired resistance mechanisms to sustained auxin-inducible protein degradation in cells and mice

Judith W. Hyle, Zhenling Liu, Shaela Fields, Jifeng Yang, Xinyan Chen, Wenjie Qi, Qiong Zhang, Byoung-Kyu Cho, Young Ah Goo, Xiuling Li, Jack E. Sublett, Qianqian Li, Liusheng He, Jonathon D. Klein, Peng Xu, , Chunliang Li

This study identifies four resistance mechanisms to sustained auxin-inducible protein degradation in human cells and mice using the AID2 system.

bioRxiv · Sep 21, 2025 · PreprintCell Biology