Shelley C. Rankin

This paper compares metagenomic sequencing with traditional culture methods for diagnosing companion animal skin infections, showing that metagenomics identifies pathogens and antibiotic resistance genes as effectively as culture-based methods and provides additional insights into microbiome composition.

The paper shows replicating Salmonella triggers TNF- and caspase-8-driven apoptosis via TLR4 and SPI-2, distinct from non-replicating Salmonella-induced pyroptosis.