Author

Dieter M. Schifferli

University of PennsylvaniaORCID 0000-0002-5540-2969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexey V. RakoviD· 1 shared Beatrice I. HerrmanniD· 1 shared Emilio MastrianiiD· 1 shared Igor E. BrodskyiD· 1 shared Justin L. RoncaioliiD· 1 shared Kodi S. RavichandraniD· 1 shared Lance W. PetersoniD· 1 shared Maxime Zamba‐Campero· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Alexey V. RakovORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Innate detection of Salmonella replication triggers caspase-8-dependent apoptosis via TLR-driven TNF signaling and NLRC4-mediated sensing of the SPI-2 Type III secretion system

Beatrice I. Herrmann, Maxime Zamba‐Campero, Reyna Garcia Sillas, Winslow Yost, Lance W. Peterson, Justin L. Roncaioli, Shelley C. Rankin, Dieter M. Schifferli, Kodi S. Ravichandran, Igor E. Brodsky

The paper shows replicating Salmonella triggers TNF- and caspase-8-driven apoptosis via TLR4 and SPI-2, distinct from non-replicating Salmonella-induced pyroptosis.

bioRxiv · Sep 10, 2025 · PreprintMicrobiology

HamHeat: A fast and simple package for calculating Hamming distance from multiple sequence data for heatmap visualization

Alexey V. Rakov, Dieter M. Schifferli, Shu-Lin Liu, Emilio Mastriani

HamHeat calculates Hamming distances for multiple sequence alignments to generate heatmaps efficiently.

bioRxiv · Mar 26, 2020 · PreprintBioinformatics