Clement Hamani

Aberrant cortical reorganization and astrogliosis underlie memory deficit post-traumatic brain injury: a longitudinal multiscale multimodal study

This study uses multiscale multimodal data integration in a mouse model of traumatic brain injury to identify biomarkers of memory deficits and network dedifferentiation.

Chronic Stress Exacerbates Long-term Microvascular Network Dysfunction Following Brain Trauma

This study shows that chronic stress worsens microvascular network dysfunction after brain trauma, reducing capillary coordination and vascular reactivity.

Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder

This study identifies PAX6 as a critical predictor of MDD using transcriptomic data from 3,114 individuals and validates its expression in PBMCs and the amygdala.

Reduction of aggressive behaviour following hypothalamic deep brain stimulation: involvement of 5-HT1A and testosterone

This study shows that hypothalamic deep brain stimulation reduces aggressive behavior in mice by modulating testosterone levels and 5-HT1A receptor density.