Author

Young Min Park

Yonsei UniversityORCID 0000-0002-7593-8461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

De‐Chen LiniD· 4 shared Chehyun NamiD· 2 shared Hua ZhaoiD· 2 shared Qiong MaoiD· 2 shared Thomas TiltoniD· 2 shared Uttam K. SinhaiD· 2 shared Yueyuan ZhengiD· 2 shared Alice SoragniiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersCancer Biology

De‐Chen LinORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

MCT4-Associated Lactate Export Defines Myeloid Metabolic Reprogramming during Head and Neck Cancer Progression

Thomas Tilton, Young Min Park, Haiqi Zhu, Chi Zhang, De‐Chen Lin

The paper identifies increased MCT4-associated lactate export in myeloid cells during HNSCC progression using single-cell RNA-sequencing and metabolic flux analysis.

bioRxiv · Oct 16, 2026 · PreprintCancer Biology

ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion

Benjamin Ziman, Talia A. Wenger, Chehyun Nam, Qian Yang, Daniel Arnaudov, Thomas Tilton, Megha Sheth, Zhixuan Jing, Yuhao Pan, Joseph A. Vargas, Yong Teng, Uttam K. Sinha, Young Min Park, De‐Chen Lin

This study identifies ETS1 as a master regulator of a hybrid EMT program in UASCC that drives metastasis and immune evasion, and shows HSP90 inhibitors can target ETS1-driven tumors.

Cancer Research · May 19, 2026Peer-reviewedCancer Biology

Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma

Jung Hyun Um, Yueyuan Zheng, Qiong Mao, Chehyun Nam, Hua Zhao, Yoon Woo Koh, Su‐Jin Shin, Young Min Park, De‐Chen Lin

This study establishes patient-derived tumor organoids (PDOs) from 31 HNSCC patients, faithfully recapitulating tumor characteristics and predicting cisplatin responses, revealing hEMT-driven resistance and AREG as a therapeutic target.

Cancer Research · Apr 22, 2025Peer-reviewedCancer Biology

Genetically Defined Organoid Models Reveal Mechanisms Driving Squamous Cell Neoplastic Evolution and Identify Potential Therapeutic Vulnerabilities

Hua Zhao, Young Min Park, Yueyuan Zheng, Qiong Mao, Casey Collet, Boyan Hu, Tianming Zhou, Luda Lin, Stephanie K. Wong, Yuhao Pan, Anette Vistoro Monreal, Uttam K. Sinha, Parish Paymon Sedghizadeh, Alice Soragni, De‐Chen Lin

bioRxiv · Jan 18, 2025 · PreprintCancer Biology