Author

Boyan Hu

Huazhong Agricultural University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Dadong DaiiD· 3 shared Dexin BoiD· 3 shared Donghai PengiD· 3 shared Shurong ZhangiD· 3 shared Yali ZhangiD· 3 shared Yayi ZhouiD· 3 shared Jinshui ZhengiD· 2 shared Ming SuniD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Dadong DaiORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

N6-Methyladenine DNA modification modulates pathogen virulence in nematodes

Dadong Dai, Shurong Zhang, Boyan Hu, Yayi Zhou, Simeng Cui, Jia Teng Sun, Yali Zhang, Xueyu Wang, Shahid Siddique, Dexin Bo, Min Zhang, Valerie Moroz Williamson, Haozhe Yao, Xinya Duan, Wentao Wu, , Ming Sun

This study identifies 6mA demethylases as key regulators of virulence in plant-parasitic nematodes and shows their potential as targets for sustainable control.

Proceedings of the National Academy of Sciences · Mar 4, 2026Peer-reviewedMolecular Biology

Targeting HIF-2α in Colorectal Cancer Reveals a Cholesterol Biosynthesis-Dependent Ferroptotic Vulnerability

Prarthana Dalal, Rashi Singhal, Boyan Hu, Drew C. Stark, Nicholas J. Rossiter, Chesta Jain, Peter Sajjakulnukit, Costas Andreas Lyssiotis, Yatrik Madhukar Shah

This study identifies a metabolic vulnerability in colorectal cancer where combining HIF-2 inhibition with cholesterol biosynthesis inhibition using statins enhances ferroptosis, offering a new therapeutic strategy.

Cancer & Metabolism · Feb 12, 2026Peer-reviewedCancer Biology

6mA demethylase Mi-NMAD-1 modulates nematode development and parasitism through the transcription factor Mi-nhr-118

Dadong Dai, Yucheng Liao, Dexin Bo, Shahid Siddique, Yayi Zhou, Boyan Hu, Shurong Zhang, Yali Zhang, Pengfei Zhu, Donghai Peng, Ming Sun, Jinshui Zheng

This study identifies Mi-NMAD-1 as an essential 6mA demethylase in nematodes, showing its role in development and parasitism through regulation of Mi-nhr-118.

bioRxiv · Dec 19, 2025 · PreprintMolecular Biology

Developmental dynamic transcriptomics reveals multiple effectors and transcription factors critical for Ditylenchus destructor parasitism

Yangyang Chen, Shurong Zhang, Yayi Zhou, Xueyu Wang, Dexin Bo, Yucheng Liao, Boyan Hu, Yali Zhang, Noha Mohamed Ashry, Donghai Peng, Ming Sun, Dadong Dai

This study presents a chromosome-level genome of Ditylenchus destructor and identifies stage-specific effectors and transcription factors critical for parasitism.

BMC Biology · Dec 18, 2025Peer-reviewedGenomics

Genetically Defined Organoid Models Reveal Mechanisms Driving Squamous Cell Neoplastic Evolution and Identify Potential Therapeutic Vulnerabilities

Hua Zhao, Young Min Park, Yueyuan Zheng, Qiong Mao, Casey Collet, Boyan Hu, Tianming Zhou, Luda Lin, Stephanie K. Wong, Yuhao Pan, Anette Vistoro Monreal, Uttam K. Sinha, Parish Paymon Sedghizadeh, Alice Soragni, De‐Chen Lin

bioRxiv · Jan 18, 2025 · PreprintCancer Biology