Lrfn2-mutant mice display suppressed synaptic plasticity and inhibitory synapse development and abnormal social communication and startle response
Yan Li, Ryunhee Kim, Yi Sul Cho, Woo Seok Song, Doyoun Kim, Kyungdeok Kim, Junyeop Daniel Roh, Changuk Chung, Hanwool Park, Esther Yang, Soo‐Jeong Kim, Jaewon Ko, Hyun Kim, Myoung‐Hwan Kim, Yong Chul Bae, Eunjoon Kim
This study investigates the role of SALM1/LRFN2 in synaptic function and behavior by analyzing Lrfn2-/- mice, finding altered synaptic plasticity, inhibitory synapse development, and social communication behaviors.
Journal of Neuroscience · May 24, 2018Peer-reviewedNeuroscience