Author

Siavash Monfared

University of CopenhagenORCID 0000-0002-7629-7977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Amin DoostmohammadiiD· 2 shared Andreas SchoenitiD· 2 shared Benoît LadouxiD· 2 shared Lucas AngeriD· 2 shared René‐Marc MègeiD· 2 shared Carine RosséiD· 1 shared Elisabetta MarangoniiD· 1 shared Fanny WodrasckaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Amin DoostmohammadiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Mechanical Tension Actively Triggers RhoA-Mediated Cell Extrusion

Fanny Wodrascka, Tianxiang Ma, Pablo Gottheil, Robin Durand, Lucas Anger, Andreas Schoenit, Mallica Pandya, M Arnaud, Tien Dang, Siavash Monfared, Guillaume Charras, René‐Marc Mège, Amin Doostmohammadi, Benoît Ladoux, Simon de Beco

This study shows mechanical tension, not just biochemical signals, actively drives cell extrusion via RhoA-mediated contractility in epithelial monolayers.

bioRxiv · Jul 8, 2026 · PreprintCell Biology

Force transmission is a master regulator of mechanical cell competition

Andreas Schoenit, Siavash Monfared, Lucas Anger, Carine Rossé, Varun Venkatesh, Lakshmi Balasubramaniam, Elisabetta Marangoni, Philippe Chavrier, René‐Marc Mège, Amin Doostmohammadi, Benoît Ladoux

This study identifies force transmission as a key factor in cell competition, showing that stronger intercellular adhesion leads to cell elimination through mechanical stress fluctuations.

Nature Materials · Mar 14, 2025Peer-reviewedBiophysics