A principal-stress rule for cell division in epithelia
Lucas Anger, Tianxiang Ma, Fanny Wodrascka, Andreas Schoenit, Kristian Thijssen, Satish Kailasam Mani, Marc-Antoine Fardin, Carine Rossé, René‐Marc Mège, Amin Doostmohammadi, Benoît Ladoux
The paper shows that cell division in epithelia follows a mechanical principal-stress rule rather than a geometric rule, as cells divide along their principal stress axis to relieve anisotropic stress.
Nature Communications · Sep 23, 2026Peer-reviewedBiophysics