An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans
Pallavi Kakade, Juan F. Burgueño, Shabnam Sircaik, Nicole O. Ponde, Jinke Li, Iuliana V. Ene, Jiwoong Kim, Shen-Huan Liang, Rebecca Yunker, Ipsita Dey, Yasutada Akiba, Shipra Vaishnava, Jonathan D. Kaunitz, Sing Sing Way, Andrew Young Koh, , Richard J. Bennett
This study identifies an IL-17-DUOX2 axis that regulates C. albicans colonization and filamentation in the gut through interactions with candidalysin toxin.
Nature Communications · May 4, 2026Peer-reviewedImmunology