Shipra Vaishnava

A gavage-fomite based method to generate mouse models with natural microbiota

This paper introduces a gavage-fomite method to generate mice with natural microbiota, showing improved immune maturation and protection against bacterial challenges compared to traditional methods.

A host-adapted commensal fungus from pet store mice drives type 2 immunity and cross-kingdom protection

This study identifies Kazachstania pintolopesii as a commensal fungus in pet store mice that induces type 2 immunity and protects against nematode infection without triggering classical anti-fungal responses.

An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans

This study identifies an IL-17-DUOX2 axis that regulates C. albicans colonization and filamentation in the gut through interactions with candidalysin toxin.

Epithelium intrinsic zinc sensor controls immune homeostasis with gut microbes via regulation of Tuft cell lineage

This study shows that zinc sensing via MTF1 in intestinal epithelial cells regulates Tuft cell lineage and immune homeostasis with gut microbes.

Low abundance members of the gut microbiome are potent drivers of immune cell education.

This study identifies low abundance gut bacteria as significant drivers of immune cell education by affecting MHC class II expression and T-cell cytokine production in mice.