ImmunologyPLoS PathogensPeer-reviewed
An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen
Bianca M. Coleman, Melissa Erin Cook, Md. Robin Khan…·Sarah L. Gaffen
1 citation
Author
Nicole O. Ponde
University of PittsburghORCID 0000-0003-2704-0451Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 30 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- ImmunologyNature CommunicationsPeer-reviewed
An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans
Pallavi Kakade, Juan F. Burgueño, Shabnam Sircaik…·Richard J. Bennett
This study identifies an IL-17-DUOX2 axis that regulates C. albicans colonization and filamentation in the gut through interactions with candidalysin toxin.
2 citations - MicrobiologybioRxivPreprint
N6-methyladenosine (m6A) RNA modification restrains antifungal immunity and is a therapeutic target in oral candidiasis
Nicole O. Ponde, Melissa Erin Cook, Isha Mehta…·Sarah L. Gaffen
This study shows that m6A RNA modification suppresses antifungal immunity in oral epithelial cells and that inhibiting the m6A pathway enhances antimicrobial peptide expression, reducing fungal burden in candidiasis.
- Molecular BiologybioRxivPreprint
The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids
Jennifer Rynne, Elena Ortiz Zapater, Paniz Khooshemehri…·Rocío T. Martínez-Nuñez
This study investigates how glucocorticoids modulate RNA binding proteins ZFP36L1 and ZFP36L2, showing their role in transcriptional and post-transcriptional gene regulation through subcellular RNA binding and localization changes.
4 citations