Emmanuelle Josselin

This study identifies CELSR2 as a regulator of epithelial-mesenchymal plasticity and oxidative phosphorylation in triple-negative breast cancer, showing its role in shaping tumor heterogeneity.

This study develops N4CART cells targeting Nectin-4 that overcome resistance to EV in solid tumors and show safety by avoiding skin toxicity.

The paper shows that inducing telomerase in p21-positive cells in aging mice lungs reduces capillary rarefaction and improves lung function by promoting microvasculature regeneration.

This study shows that telomerase expression in old mice prevents emphysema by maintaining endothelial and AT2 cell populations through increased proliferation.