Xiaorong Liu

Closed-loop optical optimization enables patterned retinal stimulation in vivo at cellular scales

This paper introduces a closed-loop optical platform for precise retinal stimulation in mice, achieving high-resolution patterned stimulation with real-time focus correction.

Vis-OCT Explorer: an open-source software for visible-light optical coherence tomography data processing

Vis-OCT Explorer processes vis-OCT data to improve image quality and measurement repeatability for retinal analysis.

Vitreous Inflammation as an Early Indicator of Retinal Ganglion Cell Loss Following Acute Optic Nerve Injury in Mice

The paper identifies vitreous hyperreflective foci (VHRFs) as an early inflammatory indicator of retinal ganglion cell loss following optic nerve injury in mice and shows IL-1 signaling inhibition reduces VHRFs and delays cell loss.

Longitudinal analysis of retinal ganglion cell damage at individual axon bundle level in mice using visible-light optical coherence tomography fibergraphy

This study uses vis-OCTF to track individual RGC axon bundle changes after ONC injury, showing swelling at 3-days and shrinking at 9-days, correlating with RGC soma loss.

Correlation between Retinal Ganglion Cell Loss and Nerve Crush Force-Impulse Established with an Instrumented Tweezers in Mice

The paper develops an instrumented tweezers system to measure optic nerve crush forces and establishes a correlation between axon loss and force-impulse in mice.